Bodybuilders and others who want to build muscle make use of Dindolyl Methane (or DIM). However there have been some recent links to health hazards that DIM could cause. DIM can cause liver damage if consumed in excess. Another risk is kidney damage, which may result in kidney failure. Many bodybuilders and athletes are concerned about the long-term health risks associated with DIM.
To increase testosterone production, most people take a diindolylmethane supplement. Testosterone has been shown to act as an anandrogen, meaning that it causes hormonal changes in tissues. DIM has been proven in studies to mimic the effects of testosterone, as well as other hormones. Certain manufacturers have added diindolylmethane (DIM) to their products to increase their marketability in male circles because men produce more testosterone than women do. The idea is that men will respond to a product that replicates the effects of natural testosterone.
Many companies market DIM as a tumor-suppressor. Diindolylmethane is a fact that it does reduce the growth of tumors in laboratory animals, however these animals were given the drug, not orally. For humans to achieve the same effect, diindolylmethane must be taken in high doses for an extended period of duration. Also, although the animals studied remained cancer-free for several years, they all developed liver disease at some point, possibly because of the high levels of diindolylmethane circulating in their system. For a thorough look at the way DIM is affecting the body, you should consult a physician.
According to the US National Institute of Environmental Health Safety and Security, the only way to show that DIM is effective in treating breast cancer is to perform an experiment where cells from healthy breast cancer cells are exposed to large doses of diindolylmethane over a period of time. Like any chemical, there are both pros and cons to using it. The ability to mimic hormones is among the advantages. This means that you could create insulin, which can inhibit cancer cell proliferation. The cons include the fact diindolylmethane also produces the potentially harmful chemical DMSO. Know more about what does diindolylmethane do now.
One of the most common claims made about diindolylmethane’s use in treatment for various illnesses is that it is an natural, antibacterial, anticancer, and anti-fungal agent. These claims were rejected by the National Institute of Health after an exhaustive review of the supporting data. According to the Institute of Chemical Technology, there were no experiments performed to support this assertion. The Institute of Chemical Safety, conducting an in-depth study of the safety profile for the firestone concluded that the data provided by pharmaceutical companies regarding the benefits of diindolylmethane to humans were not completely reliable.
Van der Goes, et. and. published their findings in the May 2021 issue of the Journal of Toxicology and Environmental Health. Van der Goes, et al., highlighted the potential risks of diindolylmethane, which includes skin rash and allergic reactions asthma attacks as along with headaches, dizziness and respiratory issues. They also stated that the recommended daily allowance for this chemical is 0.2 milligrams, or about one 10th of a teaspoon. It is not clear what the concentration is when compounded with other compounds. Because this substance has not been thoroughly tested, it is not considered to be safe at any level.
The view abstract shows that the use of diindolylmethane for cancer treatment is based on the notion that intracellular inhibition of pyruvate metabolism via flavenoids can be slowed down and prevents accumulation of oxalates and pyruvate metabolites in renal tubule cells. The drug metabiplicate toxicology studies have not proven that this chemical can cause overdose. The Food and Drug Administration approved this substance as a prescribed drug in June 1996. According to the FDA the company that makes firestone tincture is currently in the process of completing two major trials–one in Europe and the other in the United States.
The abstract of the view also indicates the use of diindolylmethane in cancer treatment is based on the concept of inhibiting intracellular inhibition by flavenoids of pyruvate metabolism and thus stopping the accumulation of adenine and oxalates within renal tubule cells. However, the drug metabiplicate toxicity studies did not present convincing evidence that consumption of this chemical can cause an overdose. In June 1996, the Food and Drug Administration approved this drug as a prescription drug. According to the FDA the manufacturer of firestone tincture is in the process of completing two major trials – one in Europe and another in the United States. According to the FDA the company that makes firestone tincture is in process of conducting two major trials in Europe and one in the United States.